Sains Malaysiana 42(9)(2013):
1345–1355
Sarcopenia
and Its Impact on Health: Do They Have Significant Associations?
(Sarkopenia dan Kesannya ke
Atas Kesihatan: Adakah Terdapat Sebarang Hubung Kait?)
S.K. Norshafarina1, M.S. Noor
Ibrahim2*, S. Suzana3, A. Mohamad
Hasnan3, M. Zahara3 & Y. Zaitun4
1Biomedical
Sciences Programme, Faculty of Health Sciences, Universiti Kebangsaan
Malaysia
Jalan Raja
Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia
2Occupational
Therapy Program, Faculty of Health Sciences, Universiti Kebangsaan
Malaysia
Jalan Raja
Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia
3Dietetics Programme,
Faculty of Health Sciences, Universiti Kebangsaan Malaysia
Jalan Raja
Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia
4Department
of Nutrition, Faculty of Medicine and Health Sciences, Universiti
Putra Malaysia
43400 Serdang,
Selangor D.E., Malaysia
Diserahkan:
10 November 2011/Diterima: 21 Mei 2013
ABSTRACT
A cross sectional study was
conducted to determine the prevalence of Sarcopenia and its association with
health profiles and oxidative stress among multiethnic older adults in an urban
area of Malaysia. Sarcopenia was assessed using Bioimpedance analysis (BIA)
and the associations between demography, socioeconomic status, lifestyle practices,
health risk factors and blood profile were examined on 388 apparently healthy
subjects aged 60 years and above. Prevalence of sarcopenia was 89.0% in men and
40.3% in women with the overall prevalence of 59.8%. It was found that
prevalence of severe sarcopenia was 13.9% and sarcopenia obese was 23.5%.
Binary logistic regression showed that there was no predictor found in men or
women. However, a decline in muscle mass was observed in sarcopenic as compared
with normal subjects. Sarcopenia is prevalent and there is a need to implement
interventional strategies to prevent sarcopenia and its associated
comorbidities.
Keywords: Elderly people; Malaysia;
muscle mass; oxidative stress; sarcopenia
ABSTRAK
Satu kajian keratan lintang telah
dijalankan bagi menentukan prevalens sarkopenia dan hubungannya dengan profil
kesihatan dan tekanan oksidatif dalam kalangan warga tua multietnik di sebuah
kawasan bandar di Malaysia. Sarkopenia dinilai menggunakan analisis bioimpedans
(BIA)
dan hubungannya dengan demografi, status sosioekonomi, amalan gaya hidup,
faktor risiko kesihatan dan profil darah telah ditentukan dalam kalangan 388
subjek berusia 60 tahun dan ke atas yang kelihatan sihat. Prevalens sarkopenia
adalah 89.0% dalam kalangan lelaki dan 40.3% dalam kalangan wanita, dengan
prevalens keseluruhan adalah 59.8%. Didapati bahawa prevalens sarkopenia teruk
adalah 13.9% dan sarkopenia obes adalah 23.5%. Analisis regresi logistik binari
menunjukkan tiada prediktor yang dijumpai bagi lelaki atau wanita. Walau bagaimanapun,
penurunan jisim otot berlaku dalam kalangan subjek sarkopenia berbanding subjek
normal. Sarkopenia adalah prevalens dan terdapat keperluan bagi implementasi
strategi pencelahan bagi mencegah sarkopenia dan komorbiditi berkaitannya.
Kata kunci: Jisim otot; Malaysia; sarkopenia;
tekanan oksidatif; warga tua
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*Pengarang untuk surat-menyurat;
email: drn00r@yahoo.com
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